My cheeks go red at the slightest thing — new products, wind, stress — but this cream has genuinely quietened all of that down. By the end of two weeks my partner actually asked what I'd changed in my routine. 🌿
Medicube Exosome Cica Cream
- Cica + Exosome technology visibly calms redness by day 14
- Lightweight, non-greasy finish layers seamlessly into any routine
- Gentle enough for sensitive, reactive skin from the very first use
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Fast shipping5–14 days
Shipping information
Free shipping to South Africa within 5 to 14 business days for orders R770 and up. Or, standard shipping to South Africa within 5 to 14 business days for R 80.00. Only applies to orders with an order value less than R770.
The Cream That Puts an End to Angry Skin
Powered by exosome technology and centella asiatica, this rich yet fast-absorbing cream dials down redness and restores your skin's natural barrier — often visibly, within a fortnight of consistent use.
Four Reasons Your Skin Will Thank You
A calming, repairing cream built for skin that needs a little more care.
Not All Calming Creams Are Equal
Most soothing creams stop at basic moisturising. This one goes further — combining barrier repair, exosome renewal, and cica calming in a single step that suits even the most sensitive skin types.
Skin That Speaks for Itself
What users noticed after consistent use.
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96%felt their redness visibly calmed after two weeks of use
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97%reported skin feeling more comfortable and hydrated from the first application
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95%said the texture felt lightweight and comfortable under their usual routine
Your Last Step Before You Rest — or Start the Day
After cleansing and toning, press a pea-sized amount gently into skin morning and evening, focusing on areas of redness or sensitivity.
Layer underneath SPF in the morning or use as your final seal-in step at night for best results.
Your questions, answered
Building confidence with clear answers to your concerns.
How often should I use this cream?
Twice daily — morning and evening — gives you the best results. Apply it as the final step of your skincare routine after serums and essences.
Is it safe for sensitive or reactive skin?
Yes, this cream is specifically formulated with soothing ingredients like cica to calm reactive skin. If your skin is particularly sensitive, do a patch test on your inner arm for 24 hours before applying to your face.
What does the cream feel like on the skin?
It has a rich but lightweight texture that absorbs without leaving a greasy residue. Most users describe the finish as soft and comfortable — not heavy or occlusive.
Can I layer it with other products?
Absolutely. Apply it after water-based serums and essences, and before SPF in the morning. It sits well under both physical and chemical sunscreens without pilling.
When can I expect to see results?
Many users notice their skin feels more comfortable and looks calmer within the first few days. More visible changes — like reduced redness and a smoother texture — typically become apparent after consistent use for around a fortnight.
What are the hero ingredients?
The two stars are exosomes — tiny delivery vessels that support skin's repair process — and centella asiatica (cica), a well-researched plant extract known for calming irritation and strengthening the skin barrier.
What skin concerns does this cream target?
It's designed for redness, irritation, a weakened skin barrier, and sensitivity. It's also a great option for skin recovering from over-exfoliation, environmental stress, or any procedure that leaves the skin reactive.
How do I fit this into my routine — before or after other actives?
Apply after any active serums (such as vitamin C or niacinamide) so it seals everything in and helps buffer any potential sensitivity. On nights when you're using a retinol or exfoliant, this cream is an excellent calming finisher.
Loved by our customers
Real feedback from real customers.
I was sceptical about the exosome hype but my skin barrier was in a terrible state after overusing acids, and this brought it back. The texture is exactly what I needed — creamy but not suffocating.
Really nice cream — it layers beautifully under my SPF and doesn't pill at all. I'd love to see a slightly lighter version for our warmer days, but the soothing effect on my rosacea-prone skin is hard to argue with.
The redness around my nose that I've had for years is noticeably less angry. I use this every morning and evening and my skin just looks calmer — more even, less blotchy.



