My skin barrier was completely wrecked from over-exfoliating and this cream brought it back to life within about ten days. The redness settled noticeably and my skin stopped feeling tight after cleansing.
Dr. Althea 345 Relief Cream
- PDRN visibly calms redness and repairs in 14 days
- Niacinamide fades blemish marks and brightens tone
- Korean vegan formula — gentle on all skin types
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Fast shipping5–14 days
Shipping information
Free shipping to South Africa within 5 to 14 business days for orders R770 and up. Or, standard shipping to South Africa within 5 to 14 business days for R 80.00. Only applies to orders with an order value less than R770.
The Cream That Calms, Repairs, and Brightens All at Once
The Dr. Althea 345 Relief Cream pairs PDRN — a regenerative ingredient borrowed from dermatology — with niacinamide to soothe irritation, fade blemish marks, and restore your skin's barrier, all in one step. Ver.2 is the upgraded formula, and your skin will notice.
Four Reasons Your Skin Will Thank You
A targeted formula built around real skin recovery — not just surface hydration.
Not All Recovery Creams Are Built the Same
Many moisturisers promise barrier support but rely on basic humectants alone. The 345 Relief Cream goes further — derma-grade PDRN, proven niacinamide, and a vegan formulation designed for real skin recovery rather than a temporary glow.
Numbers That Speak for Themselves
Based on user feedback and clinical-style testing on the Ver.2 formula.
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97%reported visibly calmer, less red skin after two weeks of use
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95%noticed a smoother, more even skin tone within 14 days
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98%said the cream absorbed quickly without leaving a greasy residue
Layer It Into Your Routine — Morning, Night, or Both
After cleansing and toning, apply a generous amount of the 345 Relief Cream to your face and neck using gentle patting motions until fully absorbed. It layers beautifully under SPF in the morning and works as the final step of your evening routine — no heavy or tacky feeling left behind.
Your questions, answered
Building confidence with clear answers to your concerns.
How often should I use the 345 Relief Cream?
You can use it twice daily — once in the morning before SPF and once at night as the last step of your routine. For very dry or compromised skin, a slightly thicker layer in the evening works well to support overnight recovery.
Is it safe for sensitive skin?
Yes. The formula is a certified Korean vegan blend specifically designed to calm and soothe irritated or reactive skin. It's free from common irritants and has been formulated to suit all skin types, including sensitive and post-procedure skin.
What does it feel like on the skin?
It applies as a soft, cushiony cream that sinks in fairly quickly without leaving a greasy or heavy film. Once absorbed, skin feels comfortable, slightly plumped, and settled — not tacky or shiny.
Can I layer it with serums and other actives?
Absolutely. Apply it as your final moisturising step, after serums and essences. Its texture makes it an excellent occlusive layer over water-based actives like hyaluronic acid or vitamin C serums, helping seal everything in.
When will I start seeing results?
Most users notice improved skin texture and reduced redness within the first week. More visible changes to blemish marks and overall skin tone typically become apparent after consistent use for 14 days or more.
What does PDRN do and why is it in a moisturiser?
PDRN (Polydeoxyribonucleotide) is a regenerative ingredient widely used in professional skin treatments to stimulate repair at a cellular level. In this cream, it helps speed up barrier recovery, reduce redness, and improve skin resilience over time — making it particularly useful after breakouts or sensitivity flare-ups.
Will it help with acne scars and dark spots?
Yes — the niacinamide in the formula is specifically included to target post-blemish marks and uneven pigmentation. It works by reducing melanin transfer to the skin's surface, gradually lightening dark spots with consistent use.
Is the 345 Relief Cream suitable for oily or acne-prone skin?
It is. The non-greasy texture means it doesn't feel heavy or pore-clogging on oily skin, and the combination of niacinamide (which helps regulate sebum) and PDRN (which supports post-breakout healing) makes it a practical option for acne-prone skin types.
Loved by our customers
Real feedback from real customers.
I wasn't expecting much from a moisturiser at this price point but the texture alone won me over — it's dense enough to feel nourishing but disappears into the skin without any greasiness. My complexion looks more even now. 🌟
Great everyday cream for sensitive skin. It doesn't sting or cause any reactivity which is rare for me. I'd love a slightly bigger tube but the formula itself is excellent.
The PDRN in this is the real deal — I've used it after a chemical peel and it sped up recovery significantly compared to my usual moisturiser. Skin felt calm and looked clearer within a week.
I have oily, acne-prone skin and was nervous about a cream feeling heavy but this is genuinely lightweight. My breakout marks have faded a lot over the past few weeks and my skin tone is much more uniform.
My girlfriend recommended this to me and I was sceptical but I've been using it as my only moisturiser for a while now and my skin looks better than it has in years. The irritation around my jawline has calmed right down.
I layer this over my niacinamide serum at night and the combination has completely transformed my skin — dark spots I've had for ages are visibly lighter. The cream itself has a slightly medicinal but pleasant scent that I've come to love.
This is my third tube. It's the only moisturiser that keeps my skin hydrated through the entire day without needing to top up. Nothing dramatic, just consistently good skin every morning when I wake up.
I appreciate that this is vegan-certified — it's genuinely hard to find K-beauty that ticks that box. The cream is lovely to apply, sinks in fast, and my skin has been noticeably less reactive since I started using it.
Used it on my neck and décolletage as well as my face and the texture improvement has been real. Skin looks plumper and the small bumps I had from shaving irritation on my neck are almost completely gone.
The Ver.2 formula is noticeably better than what I tried from the brand previously — it absorbs faster and the finish is less waxy. My post-acne marks are fading steadily and the overall radiance of my skin has improved.
I have combination skin and finding a moisturiser that works across my dry cheeks and oily T-zone without causing congestion is nearly impossible — until this one. It genuinely balances rather than just hydrating one area and suffocating the other.
It's become my go-to for those days when my skin is red and reactive. A thin layer in the morning settles everything down within a couple of hours. Not a miracle worker but reliably calming.
I started using this alongside my retinol and it's massively reduced the peeling and irritation I used to get. My skin is smoother and clearer than ever — I think the PDRN is doing a lot of the heavy lifting.
The consistency is like a soft cloud — not thick, not watery, just perfect. I use it as my final step every night and I wake up with skin that looks genuinely rested. Hard to describe but you feel it immediately.
Good moisturiser for the price. It doesn't have that heavy, suffocating feeling I get from a lot of creams — it just quietly does its job. My skin has been a lot less dry around my nose and chin.
I bought this on a whim and it's now a permanent fixture in my skincare routine. The blemish-fading effect is real — I can literally compare photos and my hyperpigmentation is less noticeable after consistent use.
My skin is extremely dry and usually I need to apply moisturiser twice during the day but with this one application in the morning is enough. The hydration genuinely lasts. Lovely product.
I was drawn in by the PDRN claim and I'm glad I tried it. My skin has been more resilient since I started using this — fewer reactions to new products and quicker recovery after I get a breakout. Solid addition to my routine.
Bought this after my dermatologist mentioned PDRN and I didn't want to spend on a clinic treatment. This cream is a fraction of the cost and my skin barrier has visibly improved — less sensitivity, less dullness, and my post-acne marks are lighter.



