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Medicube's PDRN Pink Exosome Shot Serum brings dermatology-clinic thinking home — PDRN rebuilds damaged skin while plant-derived exosomes shrink the look of pores and refine uneven texture. Available in two strengths so you can start where your skin is and build from there.
Targeted, clinical ingredients that deliver measurable change — not just a glow.
Most serums promise regeneration. This one is formulated around two clinically studied actives — PDRN and exosomes — that work on skin repair at different depths simultaneously.
Based on consumer perception studies conducted by Medicube.
After cleansing and toning, apply 2–3 drops of the serum and press gently into the skin — avoid rubbing so the exosomes can absorb fully. Start with the 2000 PPM strength if your skin is new to actives, then graduate to 7500 PPM once your barrier feels comfortable. Follow with your regular moisturiser.
Building confidence with clear answers to your concerns.
PDRN (Polydeoxyribonucleotide) is a DNA-derived ingredient that promotes cellular repair and regeneration. It signals your skin to produce more collagen, heal micro-damage, and improve overall tone — making it especially useful for post-acne marks, dullness, and loss of firmness.
Exosomes are nano-sized vesicles that carry growth factors and proteins between cells. In a serum, plant-derived exosomes deliver these signals deep into the skin's surface layers to accelerate renewal and visibly refine texture — something most conventional actives can't reach on their own.
The 2000 PPM version is ideal if you're new to PDRN or have sensitive skin — it delivers a gentler introduction to the active. The 7500 PPM is a higher-concentration formula suited for skin that already tolerates actives well and wants more intensive repair or faster results. Many users start on 2000 PPM and move up after four weeks.
Yes, the formula is designed without harsh irritants and both strengths have been tested on sensitive skin types. That said, if your skin is reactive or you're currently using strong exfoliants or retinoids, introduce the 2000 PPM strength first and watch how your skin responds over the first week.
Apply it after your toner or essence, while your skin is still slightly damp, and before heavier creams or oils. The lightweight, water-like texture absorbs quickly and won't pill under moisturiser or SPF. If you're using other actives like vitamin C or AHAs, alternate them on different evenings rather than stacking everything at once.
Most users notice improved texture and a more even complexion within 14 days of consistent daily use. For more stubborn concerns — enlarged pores, post-acne marks, or loss of elasticity — a full four-week cycle gives the PDRN enough time to support deeper cellular repair. Consistency matters more than frequency here.
It has a fluid, almost watery texture with a faint pink tint from the formulation. It absorbs within seconds, leaves no greasy residue, and sits comfortably under makeup. The finish is smooth and slightly plumping — skin feels firmer to the touch almost immediately after absorption.
Yes, it's gentle enough for twice-daily use. In the morning, follow with SPF — PDRN supports repair but doesn't protect against UV, and sun exposure can undo the cellular work the serum is doing. In the evening, it pairs well with a ceramide-rich moisturiser to lock in the regenerative benefits overnight.
Real feedback from real customers.
I started on the 2000 PPM and my skin looked noticeably clearer by the end of the second week — old acne marks that had been sitting there for months genuinely faded. The texture is so light I actually look forward to applying it every morning. 🌟
The 7500 PPM is no joke — I could feel my skin firming up within days and my pores look tighter than they have in years. I layer it under my moisturiser and it absorbs completely with no stickiness whatsoever.
I was sceptical about paying clinic prices for a serum I can use at home, but after a full month on the 7500 PPM my complexion is genuinely more even. The only reason it's four stars is that I wish it came in a slightly bigger bottle.
My skin has always been unpredictable and reactive, so I went with the 2000 PPM first — zero irritation and a real improvement in how smooth my forehead feels. The watery consistency means it works perfectly under my SPF every morning.
The plumping effect kicks in almost immediately after it absorbs — my skin just looks fuller and healthier. I'm still working through my first bottle so I can't comment on long-term results yet, but so far I'm impressed enough to already have a second one waiting.
Upgraded from the 2000 to the 7500 after a month and the difference in how fast my skin recovers from breakouts is remarkable. The faint pink colour in the bottle is such a nice touch — feels luxurious without the luxury price tag.
I bought this after my dermatologist mentioned PDRN as something to look for in at-home repair serums. My skin barrier feels significantly more resilient now — less redness in the morning and my usual dry patches have mostly disappeared.
The exosome technology is what drew me in and it genuinely delivers — my skin texture after three weeks is smoother than it's been since my twenties. I press it in with my palms and it disappears into the skin within seconds, no tackiness at all.
